Early trials suggest a host of allergies and autoimmune ailments could be treated with worm therapy, or infection with live worm-like parasites. But will it ever reach the clinic?
Chronic diarrhoea could be treated using parasitic worms, a study of monkeys has suggested.
Jim Turk initially put his symptoms down to stress.
The self-described “health nut” who was in training to run marathons suddenly found himself unable to jog for more than a couple of minutes before coming to a gasping, staggering halt.
His speech began to slur.
Turk, then in his early thirties, blamed the combined pressures of juggling a full-time job, studying for a master’s degree and his parenting responsibilities.
When he collapsed in the middle of a baseball field one sunny afternoon in 2008 while coaching his son’s team, he realized it was time to seek help.
At the hospital, magnetic resonance imaging (MRI) scans revealed plaques peppered throughout Turk’s brain and spine. The diagnosis was obvious: multiple sclerosis, the autoimmune condition in which the body eats away at its own nerve cell casings. The cure: not known yet.
A month later, Turk saw an ad on the news seeking multiple sclerosis patients to try out an unusual new treatment at the University of Wisconsin, in his hometown of Madison.
Patients were being asked to infect themselves with live pig whipworm eggs to see if the parasites alleviated any of their symptoms or slowed the spread of telltale brain and spine lesions.
“I’ve always had a research interest so I decided to put my money where my mouth is”, Turk says. “Plus I was terrified and didn’t know what to do”.
When Turk arrived at the clinic, John Fleming, a professor of neurology, presented him with a vial of clear liquid. “It tasted a little bit salty but otherwise it was just water”, says Turk. “I couldn’t see the eggs or anything”.